Question 22 - Reading Comprehension Practice Test for the HESI Exam

Referring to the attached passage, each of the following statements are examples of factual statements, except which one?

“When animals get sick, they may change their behaviour, becoming less active, for example. The study’s lead author, Patricia Lopes from the Department of Evolutionary Biology and Environmental Studies at the University of Zurich, says that previous research in wild animals has generally ignored how this change in behaviour may affect social contacts in a group and how, in turn, these changes can impact the transmission of a disease. Sick mice are not avoided, but remove themselves from the group.

To tackle this problem, Patricia Lopes and her colleagues used a novel combination of experimental manipulations of free-living mice, radio frequency tracking of animals, social network analysis and disease modelling. To simulate an infection, mice were injected with lipopolysaccharides (a component of the bacterial cell wall), which results in an immune response and generalized disease symptoms. In a paper published this week in the journal Scientific Reports, the team reveals that sick mice become disconnected from their social groups.

It is known that mice have the ability to detect other sick mice. Therefore, it was surprising to find that the animals in the same social group did not avoid the sick mouse. In fact, they went on interacting with the sick mouse and other mice more or less in the same way as before the experimental infection. “It was the sick mouse that removed itself from the group”, emphasizes Lopes. She suggests that such a change in the behaviour of the sick mouse may protect relatives in the same group from catching the disease, which could be beneficial from an evolutionary perspective.

Speed and extent of disease spread are greatly reduced.

In a further step, the researchers used mathematical models to predict how an infectious disease would spread considering the changes in behaviour of the sick animals. “When we account for the behavioural changes and how they affect social contacts, we find that the speed and the extent of disease spread are greatly reduced,” says Lopes.”

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