Which of the following patients is at highest risk for transfusion-related acute lung injury (TRALI)?
a 27-year-old female in respiratory failure secondary to pulmonary infection
a 67-year-old female with sickle cell anemia and hemoglobin 5.3 g/dL
a 45-year-old male in acute hypovolemic shock after blunt thoracic injury
a 53-year-old male with cardiovascular overload and heart failure
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